Can you use tretinoin and azelaic acid together?

Yes! Tretinoin and azelaic acid make a great combination . If your skin concerns include acne, wrinkles, and uneven skin tone, this duo could potentially be part of your solution.

Can you use tretinoin and azelaic acid together for melasma?

Clinical studies of patients with melasma have shown that topical 20 percent azelaic acid is superior to 2 percent hydroquinone and as effective as 4 percent hydroquinone without the latter's undesirable side effects. Tretinoin appears to enhance this effect of azelaic acid .

Should I apply azelaic acid before or after tretinoin?

It depends. If you're using two separate products, apply the one with the thinnest consistency first—following the general rule of thumb of applying from thinnest to thickest. This means you should apply azelaic acid before tretinoin . The other way around is also possible. This is because tretinoin can make the skin more sensitive to the sun, so it is best to apply it at night and follow it with azelaic acid and moisturizer. Applying tretinoin first allows it to penetrate the skin and then follows it with azelaic acid for additional benefits.